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Individuals experience a reduction of the symptoms which are the focus of the treatments, for example, Sciatica, low back, neck, knee, arthritis and cancer pain, cancer-related fatigue, constipation, nausea, headaches and migraines, anxiety, depression, insomnia and itching of the skin. Many Acupuncture recipients report a sense of stress reduction, peace, ease, and well-being as treatments have been said to release endorphins.